Deep infiltrating endometriosis

There was an interesting study from a French group in the on-line version of Fertility and Sterility this week.  The researchers compared the clinical records of 229 women with endometriosis; 98/229 had severe or "deep infiltrating endometriosis", 131/229 had more superficial patterns.  They found <!--more---> that patients with DIE had: a positive family history of endometriosis (odds ratio [OR] = 3.2); more absenteeism from school during menstruation (OR = 1.7; 95% CI: 1–3), OCP treatment for dysmenorrhea (OR = 4.5).  Dr Chapron, the senior author, doubted whether diagnosing endometriosis earlier will eventually lead to fewer cases of DIE and less need for surgery.

We do not have the full paper as yet.  It will be interesting to see - if the information is available - (1) how many girls had severe and constant pain from the age of onset of their menstrual periods (menarche). In the denervation-reinnervation view, that implies any injury to pelvic nerves takes place before the age of 12. Pain is severe at menarche because that is when oestrogen-dependent changes in pelvic blood flow, take place.  (2) What proportion of these young girls had sustained bowel problems, either in infancy associated with bottle-feeding or toilet training, or, in subsequent years ? If bowel habits do not change then the disease will simply "progress". Finally, (3) are there any other potential sources of injury to pelvic nerves in these patients ?