Now a Belgian group confirms the presence of endometrial nerve fibres in women with minimal endometriosis. Importantly they have started to characterise the nature of these nerves by using a panel of antibodies to stain for them in the lining of the womb. http://www.ncbi.nlm.nih.gov/pubmed/19690351?ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Abnormal nerve fibres are now described in isthmic myometrium, cervix, uterosacral ligaments, vagina, retroperitoneum, endometrium and endometrial deposits as well - in "endometriosis". Every anatomical structure at the junction of the uterus and vagina contains abnormal nerve fibres in these women. Potential causes include injuries at vaginal delivery, persistent physical efforts during defaecation (particularly in nulliparae) and direct injuries to autonomic nerves between the brain and pelvis. http://www.bristolanatomycourse.co.uk/
http://www.ncbi.nlm.nih.gov/pubmed/15325003?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
The authors do not say where thes abnormal nerve fibres originate. Neither do they say what they believe is the source of pain in "endometriosis" - is it the endometriosis, nerve fibres or both ?
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Erosive lichen planus and reinnervation
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Oral lichen planus is a difficult and distressing condition. It produces
painful plaques throughout the oral cavity. No-one knows the cause.
A new paper fr...
1 year ago
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